histopathology of post-transplant liver biopsies, the first report from iran

نویسندگان

bita geramizadeh transplant research center, shiraz university of medical sciences, shiraz, ir iran; department of pathology, shiraz university of medical sciences, shiraz, ir iran; department of pathology, shiraz university of medical sciences, 71345-1864 shiraz, ir iran. tel: +98-7116474331, fax: +98-7116474331

dorna motevalli transplant research center, shiraz university of medical sciences, shiraz, ir iran

saman nikeghbalian department of surgery, transplant center, shiraz university of medical sciences, shiraz, ir iran

seyed ali malek hosseini department of surgery, transplant center, shiraz university of medical sciences, shiraz, ir iran

چکیده

background evaluation of a transplanted liver by imaging techniques and enzyme changes is sensitive to hepatocellular or biliary problems, but in most instances liver allograft biopsies are performed in order to find out the final reason for these changes. objectives it’s been about 17 years (with more than 1326 cases) since the first liver transplantation in the namazi hospital of shiraz university of medical sciences while during the last five years the number of post liver transplant biopsies have increased. until now there has been no report of the pathological results of post liver transplant needle biopsies from iran. materials and methods during the last 5 years, there have been 382 post liver transplant biopsies. we studied the clinical charts and pathological results of all needle biopsies. results a total of 382 needle biopsies were performed on 287 patients aged between 1 and 64 years old. the earliest specimen was obtained within the first few hours following transplantation, and the last was gathered 3209 days (261 ± 523) post-transplantation. acute rejection was the most common diagnosis, which occurred in 180 (47%) of specimens. among other complications were vascular problems (8.6%), preservation/reperfusion (i/r) injury (7%), chronic rejection (5.2%), biliary injury/obstruction (3.4%), recurrence of primary disease (2.6%), drug-induced hepatic injury (1.8%), cirrhosis (1.6%), sepsis (1.4%), cytomegalovirus hepatitis (1.4%), post-transplantation lymphoproliferative disease (1%) and venous outflow obstruction (0.5%). conclusions the most common pathological diagnosis of post-transplant liver needle biopsies has been acute rejection, followed by ischemia due to hepatic artery thrombosis, preservation/reperfusion injury, and chronic rejection.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Histopathology of Post-Transplant Liver Biopsies, the First Report From Iran

BACKGROUND Evaluation of a transplanted liver by Imaging techniques and enzyme changes is sensitive to hepatocellular or biliary problems, but in most instances liver allograft biopsies are performed in order to find out the final reason for these changes. OBJECTIVES It's been about 17 years (with more than 1326 cases) since the first liver transplantation in the Namazi Hospital of Shiraz Uni...

متن کامل

First report of Chromelosporium fulvum from Iran

During spring 2011, some fungal isolates were recovered from sterilized soil (Fig. 1, A) or vermiculite, in pots and flats in greenhouses in Shiraz University, using malt extract agar and potato dextrose agar (Fig. 1, B). Anamorphic characteristics such as conidiophores and conidia were investigated. Conidiophores 125–1350 × 7.5–15 µm, hyaline, erect, broad, septate, branched once, twice (Fig. ...

متن کامل

First report of Strobilomyces strobilaceous from Iran

In the framework of collection and identification of bolete fungi of Iran, one specimen from the genus Strobilomyces was collected and identified as Strobilomyces strobilaceus (Scop.) Berk., based on Knudsen & Vesterholt (2008).

متن کامل

First report of Aquanectria penicillioides from Iran

During 2015–16, the presence of micromycetes species in aquatic ecosystems was studied in Iran. Samples were collected from rivers, lakes and wetlands. For isolation, agar disks were transferred to plates containing water samples. The plates were incubated at 25­–27° C for 21 days in 12 h light/12 h dark condition. Then from the mycelium grown on the agar disks, pure cultures were obtained. Fin...

متن کامل

First report of Paecilomyces marquandii from Iran

During 2008, the presence of Paecilomyces species was studied in fields in Fars province. Soil samples were collected from 0–20 cm depth. The isolates were recovered using a soil dilution plate method directly from soil. Isolation was performed from soil using malt extract agar, rice agar, oat-meal agar and potato dextrose agar. Anamorphic characteristics such as morphology of conidiophores, ph...

متن کامل

منابع من

با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید


عنوان ژورنال:
hepatitis monthly

جلد ۱۳، شماره ۶، صفحات ۰-۰

کلمات کلیدی

میزبانی شده توسط پلتفرم ابری doprax.com

copyright © 2015-2023